Cocaine Can Cause Aceable - University Of Massachusetts Amherst Graduate Programs Upon ingestion, cocaine impairs the brain’s. Cocaine + alcohol can cause toxic effects on the heart. Cocaine + heroin can lead to a heroin overdose, which can be deadly. Cocaine + lsd/psilocybin/cannabis can increase. When cocaine is injected in combination with heroin, sometimes called “speedballing,” there is an increased risk of toxicity, overdose, and death.
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